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Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

Acott T.S.; Fautsch M.P.; Mao W.; Ethier C.R.; Huang A.S.; Kelley M.J.; Aga M.; Bhattacharya S.K.; Borras T.; Bovenkamp D.; Chowdhury U.R.; Clark A.F.; Dibas M.I.; Du Y.; Elliott M.H.; Faralli J.A.; Gong H.; Herberg S.; Johnstone M.A.; Kaufman P.L.; Keller K.E.; Kelly R.A.; Krizaj D.; Kuehn M.H.; Li H.L.; Lieberman R.; Lin S.C.; Liu Y.; McDonnell F.S.; McDowell C.M.; McLellan G.J.; Mzyk P.; Nair K.S.; Overby D.R.; Peters D.M.; Raghunathan V.; Rao P.V.; Roddy G.W.; Sharif N.A.; Shim M.S.; Sun Y.; Thomson B.R.; Toris C.B.; Willoughby C.E.; Zhang H.F.; Freddo T.F.; Fuchshofer R.; Hill K.R.; Karimi A.; Kizhatil K.; Kopcyznski C.C.; Liton P.; Patel G.; Peng M.; Pattabiraman P.P.; Prasanna G.; Reina-Torres E.; Samples E.G.; Samples J.R.; Steel C.L.; Strohmaier C.A.; Subramanian P.; Sugali C.K.; van Batenburg-Sherwood J.; Wong C.; Youngblood H.; Zode G.S.; White E.; Stamer W.D.


  • 2024
  • Investigative Ophthalmology and Visual Science
View publication
  • Therapeutic Area

    Glaucoma

  • Categories

    Preclinical development

  • Affiliations

    Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Oregon, Portland, United States; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States; Department of Ophthalmology, Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, United States; Departments of Biochemistry and Molecular Biology and Pharmacology and Toxicology, Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, United States; Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, Atlanta, GA, United States; Hamilton Glaucoma Center, The Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, CA, United States; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Florida, United States; University of North Carolina, Chapel Hill, NC, United States; BrightFocus Foundation, Clarksburg, MD, United States; North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, United States; Glaucoma Research, Ophthalmology Discovery, AbbVie, Irvine, CA, United States; Morsani College of Medicine, University of South Florida, Tampa, FL, United States; Department of Ophthalmology and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin–Madison, Wisconsin, Madison, United States; Department of Ophthalmology, Boston University School of Medicine, Boston, MA, United States; Department of Ophthalmology & Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, United States; Department of Ophthalmology, University of Washington, Seattle, WA, United States; Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, Madison, WI, United States; Department of Ophthalmology, Duke University, Durham, NC, United States; Department of Biomedical Engineering, Duke University, Durham, NC, United States; Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, United States; Department Ophthalmology and Visual Sciences, Iowa City VA Center for Prevention and Treatment of Visual Loss, University of Iowa, Iowa City, IA, United States; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, United States; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA, United States; John Moran Eye Center, University of Utah, Salt Lake City, UT, United States; Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin–Madison, Madison, WI, United States; Deptartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States; Department of Bioengineering, Imperial College of London, London, United Kingdom; Department of Ophthalmology, Novartis Institutes for BioMedical Research, Cambridge, MA, United States; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, United States; Global Alliances and Collaborations, Ophthalmology Innovation Center, Santen Inc., Emeryville, CA, United States; Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, United States; Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States; Department of Ophthalmology and Visual Sciences, Ohio State University Wexner Medical Center, Columbus, OH, United States; Genomic Medicine, Biomedical Sciences Research Institute, Ulster University, Northern Ireland, Coleraine, United Kingdom; Department of Biomedical Engineering, Northwestern University, Evanston, IL, United States; MCP Health Sciences University, Westport, MA, United States; Institute for Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany; Department of Ophthalmology and Visual Science, Ohio State University, Columbus, OH, United States; Aerie Pharmaceuticals, Inc., Durham, NC, United States; Department of Ophthalmology and Genetics Medicine Research, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States; Western Glaucoma Foundation, Olympia, WA, United States; Washington State College of Medicine, Spokane, WA, United States; Qlaris Bio, Inc., Wellesley, MA, United States; Department of Ophthalmology and Optometry, Kepler University Hospital, Johannes Kepler University, Linz, Austria; Department of Ophthalmology, University of California at Irvine, Irvine, CA, United States

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022